Product Description: 2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro[1][2].
Applications: COVID-19-immunoregulation
Formula: C16H16O4
References: [1]Bénédicte Portet, et al. Activity-guided isolation of antiplasmodial dihydrochalcones and flavanones from Piper hostmannianum var. berbicense. Phytochemistry. 2007 May;68(9):1312-20. /[2]Cerutti ML,et al. Effects of 2',6'-dihydroxy-4'-methoxydihidrochalcone on innate inflammatory response. Naunyn Schmiedebergs Arch Pharmacol. 2020 Nov;393(11):2061-2072.
CAS Number: 35241-55-5
Molecular Weight: 272.30
Research Area: Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Parasite