Product Description: 2'-Fucosyllactose (2'-FL) is an oligosaccharide that could be derived from human milk. 2'-Fucosyllactose regulates the expression of CD14, alleviates colitis and regulates the gut microbiome. 2'-Fucosyllactose stimulates T cells to increase IFN-γ production and decreases IL-6, IL-17, and TNF-α production of cytokines[1][2].
Applications: COVID-19-immunoregulation
Formula: C18H32O15
References: [1]He Y, et, al. The human milk oligosaccharide 2'-fucosyllactose modulates CD14 expression in human enterocytes, thereby attenuating LPS-induced inflammation. Gut. 2016 Jan;65(1):33-46./[2]Eiwegger T, et, al. Human milk--derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro. Pediatr Res. 2004 Oct;56(4):536-40.
CAS Number: 41263-94-9
Molecular Weight: 488.44
Compound Purity: 99.95
Research Area: Infection; Inflammation/Immunology
Solubility: H2O : 50 mg/mL (ultrasonic)
Target: Interleukin Related;TNF Receptor