2-Ketoglutaric acid (Sodium), CAS 22202-68-2

Product Description: 2-Ketoglutaric acid Sodium (Alpha-Ketoglutaric acid Sodium) is an intermediate in the production of ATP or GTP in the Krebs cycle. 2-Ketoglutaric acid Sodium also acts as the major carbon skeleton for nitrogen-assimilatory reactions. 2-Ketoglutaric acid Sodium is a reversible inhibitor of tyrosinase (IC50=15 mM)[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C5H5NaO5

References: [1]Gou L, et al. The effect of alpha-ketoglutaric acid on tyrosinase activity and conformation: Kinetics and molecular dynamics simulation study. Int J Biol Macromol. 2017 Dec;105(Pt 3):1654-1662./[2]Huergo LF, et al. The Emergence of 2-Oxoglutarate as a Master Regulator Metabolite. Microbiol Mol Biol Rev. 2015 Dec;79(4):419-35.

CAS Number: 22202-68-2

Molecular Weight: 168.08

Research Area: Metabolic Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite;Tyrosinase

• SKU: MEXHY-W013636A-100
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W013636A-100
• Green Labware: No
• Package Unit: 100 mg
• Quantity Unit: STK