2-Methylquinazolin-4-ol, CAS 1769-24-0

Product Description: 2-Methylquinazolin-4-ol is a potent competitive poly(ADP-ribose) synthetase inhibitor, with a Ki of 1.1 μM. 2-Methylquinazolin-4-ol mammalian aspartate transcarbamylase (ATCase) inhibitor, with 0.20 mM[1][2].

Applications: Cancer-programmed cell death

Formula: C9H8N2O

References: [1]S Yoshida, et al. Production of 2-methyl-4[3H]-quinazolinone, an inhibitor of poly(ADP-ribose) synthetase, by bacterium. J Antibiot (Tokyo). 1991 Jan;44(1):111-2./[2]Mahmoud Balbaa, et al. Inhibition of mammalian aspartate transcarbamylase by quinazolinone derivatives. J Enzyme Inhib Med Chem. 2008 Aug;23(4):483-92.

CAS Number: 1769-24-0

Molecular Weight: 160.17

Compound Purity: 99.98

Research Area: Others

Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL

Target: PARP

• SKU: MEXHY-W051513-500
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W051513-500
• Green Labware: No
• Package Unit: 500 mg
• Quantity Unit: STK