4-Hydroxyestrone, CAS 3131-23-5

Product Description: 4-Hydroxyestrone (4-OHE1), an estrone metabolite, has strong neuroprotective effect against oxidative neurotoxicity. 4-Hydroxyestrone increases cytoplasmic translocation of p53 resulting from SIRT1-mediated deacetylation of p53. 4-Hydroxyestrone has little estrogenic activity[1].

Applications: Neuroscience-Neuromodulation

Formula: C18H22O3

References: [1]Hye Joung Choi, et al. 4-Hydroxyestrone, an Endogenous Estrogen Metabolite, Can Strongly Protect Neuronal Cells Against Oxidative Damage. Sci Rep. 2020 Apr 29;10(1):7283.

CAS Number: 3131-23-5

Molecular Weight: 286.37

Compound Purity: 99.0

Research Area: Neurological Disease

Solubility: 10 mM in DMSO

Target: Endogenous Metabolite

• SKU: MEXHY-W009300-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-W009300-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK