Product Description: 4β-Hydroxywithanolide E, isolated from Physalis peruviana L., inhibits adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion. 4β-Hydroxywithanolide E is an adipogenesis inhibitor and inhibits PPARγ, C/EBPα, and the adipocyte-specific molecule aP2 mRNA expression[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C28H38O8
References: [1]Momochika Kumagai, et al. 4β-Hydroxywithanolide E and withanolide E from <i>Physalis peruviana</i> L. inhibit adipocyte differentiation of 3T3-L1 cells through modulation of mitotic clonal expansion. J Nat Med. 2021 Jan;75(1):232-239.
CAS Number: 54334-04-2
Molecular Weight: 502.60
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: PPAR