Product Description: 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone is a natural product that can be extracted from B. papyrifera. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone has potent anti-proliferation effects on ER-positive breast cancer cells, with an IC50 value of 4.41 μM for MCF-7 cells. 5,7,3',4'-Tetrahydroxy-3-methoxy-8,5'-diprenylflavone also reduces the tumor growth in the BCAP-37 xenograft[1].
Applications: Cancer-programmed cell death
Formula: C26H28O7
References: [1]FujiangGuo, et al. Prenylflavone derivatives from Broussonetia papyrifera, inhibit the growth of breast cancer cells in vitro and in vivo. Phytochemistry Letters. Volume 6, Issue 3, August 2013, Pages 331-336.
CAS Number: 1353676-65-9
Molecular Weight: 452.50
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Others