Product Description: 5'-Guanylic acid disodium salt (5'-GMP disodium salt) is composed of guanine, ribose, and phosphate moieties and it is a nucleotide monomer in messenger RNA. Guanosine derivatives are involved in intracellular signal transduction and have been identified in repetitive genomic sequences in telomeres, in ribosomal DNA, immunoglobulin heavy‐chain switch regions, and in the control regions of proto-oncogenes[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C10H12N5Na2O8P
References: [1]Lan T, et al. Type II cGMP-dependent protein kinase phosphorylates EGFR at threonine 669 and thereby inhibits its activation. Biochem Biophys Res Commun. 2019 Aug 6.
CAS Number: 5550-12-9
Molecular Weight: 407.18
Compound Purity: 98.0
Research Area: Others
Solubility: DMSO : < 1 mg/mL (ultrasonic;warming;heat to 80°C)/H2O : 50 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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