Product Description: 6,8-Diprenylorobol, a prenylated isoflavone, is a nature product that could be isolated from the leaves of Cudrania tricuspidata. 6,8-Diprenylorobol antiproliferative effect and induces apoptosis through activation of p53 and generation of ROS[1][2].
Applications: Cancer-Kinase/protease
Formula: C25H26O6
References: [1]Choi YJ, et, al. 6,8-Diprenylorobol induces apoptosis in human colon cancer cells via activation of intracellular reactive oxygen species and p53. Environ Toxicol. 2021 May;36(5):914-925./[2]Tuan Anh HL, et, al. Prenylated isoflavones from Cudrania tricuspidata inhibit NO production in RAW 264.7 macrophages and suppress HL-60 cells proliferation. J Asian Nat Prod Res. 2017 May;19(5):510-518.
CAS Number: 66777-70-6
Molecular Weight: 422.47
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Akt;Apoptosis;Bcl-2 Family;Caspase;ERK;JNK;p38 MAPK;Reactive Oxygen Species
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