Product Description: 7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2].
Applications: Cancer-programmed cell death
Formula: C15H12O5
References: [1]Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14./[2]Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762.
CAS Number: 847375-46-6
Molecular Weight: 272.25
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis