Product Description: 7-Hydroxyflavanone is a potent inhibitor of aromatase (CYP19) activity with the IC50 of 65 μM. 7-Hydroxyflavanone exerts various biological effects, including anticarcinogenic, antioxidant and (anti-)estrogenic effects, and modula
Applications: Cancer-programmed cell death
Formula: C15H12O3
References: [1]Sanderson JT, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9. /[2]J Thomas Sanderson, et al. Induction and inhibition of aromatase (CYP19) activity by natural and synthetic flavonoid compounds in H295R human adrenocortical carcinoma cells. Toxicol Sci. 2004 Nov;82(1):70-9.
CAS Number: 6515-36-2
Molecular Weight: 240.25
Compound Purity: 99.59
Research Area: Cancer; Endocrinology
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: Cytochrome P450