Product Description: 7-Hydroxyflavone is a flavonoid isolated from Clerodendrum phlomidis, with anti-inflammatory activity. 7-Hydroxyflavone protects renal cells from nicotine (NIC)-associated cytotoxicity via the ERK/Nrf2/HO-1 pathway[1][2].
Applications: COVID-19-immunoregulation
Formula: C15H10O3
References: [1]Sengupta B, et al. Differential roles of 3-Hydroxyflavone and 7-Hydroxyflavone against nicotine-induced oxidative stress in rat renal proximal tubule cells. PLoS One. 2017 Jun 22;12(6):e0179777./[2]Vinutha K, et al. Aqueous extract from Madhuca indica bark protects cells from oxidative stress caused by electron beam radiation: in vitro, in vivo and in silico approach. Heliyon. 2019 May 30;5(5):e01749.
CAS Number: 6665-86-7
Molecular Weight: 238.24
Compound Purity: 99.84
Research Area: Inflammation/Immunology
Solubility: DMSO : 125 mg/mL (ultrasonic)
Target: ERK;Keap1-Nrf2
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