Product Description: 7-Methylsulfinylheptyl isothiocyanate is an activator for MAPK signaling pathway, which downregulates the melanogenesis related proteins and suppresses the melanin synthesis in B16-F1 cells. 7-Methylsulfinylheptyl isothiocyanate induces autophagy. 7-Methylsulfinylheptyl isothiocyanate is an inducer for phase II enzyme, which exhibits chemoprotective effect against carcinogen. 7-Methylsulfinylheptyl isothiocyanate can be used as cosmetic ingredient for skin whitening and anti-inflammation[1][2].
Applications: COVID-19-immunoregulation
Formula: C9H17NOS2
References: [1]Rose P, et al., 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 2000 Nov;21(11):1983-8. /[2]Kim AJ, et al., Effect of 7-Methylsulfinylheptyl Isothiocyanate on the Inhibition of Melanogenesis in B16-F1 Cells. Life (Basel). 2021 Feb 20;11(2):162.
CAS Number: 129244-98-0
Molecular Weight: 219.37
Research Area: Cancer; Inflammation/Immunology
Target: Autophagy;p38 MAPK
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