Product Description: 8-Hydroxygenistein (8-OHG) is an antioxidant that can effectively scavenge nitric oxide (NO) and superoxide anion (O₂⁻). 8-Hydroxygenistein belongs to ortho-dihydroxy isoflavones (ODI) and is abundantly present in dark soy sauce and light soy sauce. Its antioxidant activity is stronger than that of its parent compound genistein (HY-14596). The content of 8-Hydroxygenistein is positively correlated with the antioxidant capacity of soy sauce (r = 0.959), and it remains highly stable even after being heated in boiling water for 60 minutes. During the brewing and storage of soy sauce, 8-Hydroxygenistein effectively prevents oxidative damage, making it promising for use in food antioxidant research.
Applications: Metabolism-sugar/lipid metabolism
Formula: C15H10O6
References: [1]Esaki H, et al. Potent antioxidative o-dihydroxyisoflavones in soy sauces and their antioxidative activities[J]. 2002./[2]Shao J, et al. Synthesis, characterization, and antioxidant activity of 8-hydroxygenistein[J]. Natural Product Communications, 2020, 15(1): 1934578X20901399.
CAS Number: 13539-27-0
Molecular Weight: 286.24
Research Area: Others
Target: NO Synthase;Reactive Oxygen Species
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