Product Description: Actiphenol is an antibiotic against coxsackievirus B3 and influenza A virus (IC50s = 14.37 and 34.4 µg/mL, respectively). Actiphenol is also an aromatic ketone that exhibits weak eukaryotic translation inhibiton activity, which is found in Streptomyces species. Actiphenol can be used as a key intermediate to synthesize Cycloheximide (HY-12320)[1][2].
Applications: COVID-19-anti-virus
Formula: C15H17NO4
References: [1]Ji XY, et al. Synthesis and antiviral activities of synthetic glutarimide derivatives. Chem Pharm Bull (Tokyo). 2010 Nov;58(11):1436-41. /[2]Yin M, et al. Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase. Org Lett. 2014 Jun 6;16(11):3072-5.
CAS Number: 526-02-3
Molecular Weight: 275.30
Research Area: Infection
Target: Antibiotic;Drug Intermediate;Influenza Virus
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