Andrographolide, CAS 5508-58-7

Product Description: Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Andrographolide has antiviral effects.

Applications: Cancer-programmed cell death

Formula: C20H30O5

References: [1]Zhai ZJ, et al. Andrographolide suppresses RANKL-induced osteoclastogenesis in vitro and prevents inflammatory bone loss in vivo. Br J Pharmacol. 2014 Feb;171(3):663-75./[2]Gupta S, et al. Broad-spectrum antiviral properties of andrographolide. Arch Virol. 2017 Mar;162(3):611-623.

CAS Number: 5508-58-7

Molecular Weight: 350.45

Compound Purity: 99.89

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 0.1 mg/mL (ultrasonic)

Target: Autophagy;Influenza Virus;NF-κB;Parasite;SARS-CoV

• SKU: MEXHY-N0191-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N0191-10.1
• Package Unit: 10mM/1mL
• Quantity Unit: STK