Product Description: Artemisinin (Qinghaosu), a sesquiterpene lactone, is an anti-malarial agent isolated from the aerial parts of Artemisia annua L. plants[1]. Artemisinin inhibits AKT signaling pathway by decreasing pAKT in a dose-dependent manner. Artemisinin reduces cancer cell proliferation, migration, invasion, tumorigenesis and metastasis and has neuroprotective effects[2].
Applications: Cancer-Kinase/protease
Formula: C15H22O5
References: [1]Zeng Z, et al. Artemisinin protects PC12 cells against β-amyloid-induced apoptosis through activation of the ERK1/2 signaling pathway. Redox Biol. 2017 Apr 4;12:625-633./[2]Lin SP, et al. Artemisinin Prevents Glutamate-Induced Neuronal Cell Death Via Akt Pathway Activation. Front Cell Neurosci. 2018 Apr 20;12:108.
CAS Number: 63968-64-9
Molecular Weight: 282.33
Compound Purity: 99.03
Research Area: Cancer; Infection; Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)/H2O : < 0.1 mg/mL (ultrasonic)
Target: Akt;Ferroptosis;HCV;Parasite
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