Astin B, CAS 151201-76-2

Product Description: Astin B is a orally active and potent cyclic pentapeptide, that can be isolated from Aster tataricus. Astin B has hepatotoxic effects in vitro and in vivo and that hepatic injury was primarily mediated by apoptosis in a mitochondria/caspase-dependent manner. Astin B induces autophagy in L-02 cells, increases LC3-II and decreases p62 expression[1].

Applications: Metabolism-sugar/lipid metabolism

Formula: C25H33Cl2N5O7

References: [1]Wang L, et al. Astin B, a cyclic pentapeptide from Aster tataricus, induces apoptosis and autophagy in human hepatic L-02 cells. Chem Biol Interact. 2014 Nov 5;223:1-9.

CAS Number: 151201-76-2

Molecular Weight: 586.46

Research Area: Metabolic Disease

Solubility: H2O

Target: Apoptosis;Atg8/LC3;Autophagy;Bcl-2 Family;Caspase;JNK;p62;Reactive Oxygen Species

• SKU: MEXHY-P3148-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-P3148-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK