Product Description: Baicalein (5,6,7-Trihydroxyflavone) is a xanthine oxidase inhibitor with an IC50 value of 3.12 μM.
Applications: Cancer-Kinase/protease
Formula: C15H10O5
References: [1]Shieh DE,et al. Antioxidant and free radical scavenging effects of baicalein, baicalin and wogonin. Anticancer Res. 2000 Sep-Oct;20(5A):2861-5./[2]Patwardhan RS, et al. Baicalein exhibits anti-inflammatory effects via inhibition of NF-κB transactivation. Biochem Pharmacol. 2016 May 15;108:75-89./[3]Ma X, et al. Baicalein suppresses metastasis of breast cancer cells by inhibiting EMT via downregulation of SATB1 and Wnt/β-catenin pathway.
Drug Des Devel Ther. 2016 Apr 18;10:1419-41./[4]Kong EK, et al. A novel anti-fibrotic agent, baicalein, for the treatment of myocardial fibrosis in spontaneously hypertensiverats. Eur J Pharmacol. 2011 May 11;658(2-3):175-81.
CAS Number: 491-67-8
Molecular Weight: 270.24
Compound Purity: 99.13
Research Area: Cancer
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Ferroptosis;Influenza Virus;Xanthine Oxidase
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