Product Description: Bindarit (AF2838) is a selective inhibitor of the monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7, and MCP-2/CCL8, and no effect on other CC and CXC chemokines such as MIP-1α/CCL3, MIP-1β/CCL4, MIP-3/CCL23. Bindarit also has anti-inflammatory activity[1].
Applications: COVID-19-immunoregulation
Formula: C19H20N2O3
References: [1]Grassia, G., et al., The anti-inflammatory agent bindarit inhibits neointima formation in both rats and hyperlipidaemic mice. Cardiovasc Res, 2009. 84(3): p. 485-93./[2] Zoja C, Bindarit retards renal disease and prolongs survival in murine lupus autoimmune disease. Kidney Int. 1998 Mar;53(3):726-34.
CAS Number: 130641-38-2
Molecular Weight: 324.37
Compound Purity: 99.53
Research Area: Inflammation/Immunology; Neurological Disease; Cancer; Endocrinology
Solubility: DMSO : ≥ 46 mg/mL
Target: CCR
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