Product Description: Burnettramic acid A is an antibiotic, which can be isolated from Aspergillus burnettii. Burnettramic acid A exhibits antibacterial and antifungal activities, with IC50 of 0.2, 0.5, 2.3 and 5.9 μg/mL, for Saccharomyces cerevisiae, Candida albicans, Bacillus subtilis and Staphylococcus aureus, respectively. Burnettramic acid A exhibits cytotoxicity in cancer cell NS-1 with IC50 of 13.8 μg/mL[1].
Applications: COVID-19-immunoregulation
Formula: C41H71NO12
References: [1]Li H, et al., Discovery and Heterologous Biosynthesis of the Burnettramic Acids: Rare PKS-NRPS-Derived Bolaamphiphilic Pyrrolizidinediones from an Australian Fungus, Aspergillus burnettii. Org Lett. 2019 Mar 1;21(5):1287-1291.
CAS Number: 2334483-46-2
Molecular Weight: 770.00
Research Area: Infection
Target: Antibiotic;Bacterial;Fungal