Product Description: Cavidine ((+)-Cavidine) is a selective COX-2 inhibitor which possesses anti-inflammatory activity. Cavidine can be used for the research of skin injuries, hepatitis, cholecystitis, and scabies. Cavidine ameliorates LPS (HY-D1056)-induced acute lung injury via NF-κB signaling pathway[1][2][3].
Formula: C21H23NO4
References: [1]Niu X, et, al. Anti-inflammatory effects of cavidine in vitro and in vivo, a selective COX-2 inhibitor in LPS-induced peritoneal macrophages of mouse. Inflammation. 2015 Apr;38(2):923-33./[2]Niu X, et, al. Protective effect of cavidine on acetic acid-induced murine colitis via regulating antioxidant, cytokine profile and NF-κB signal transduction pathways. Chem Biol Interact. 2015 Sep 5:239:34-45./[3]Niu X, et, al. Cavidine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via NF-κB Signaling Pathway in vivo and in vitro. Inflammation. 2017 Aug;40(4):1111-1122.
CAS Number: 32728-75-9
Molecular Weight: 353.41
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: COX
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