Chaetomellic acid A, CAS 148796-51-4

Product Description: Chaetomellic acid A can be isolated from Chaetomella acutiseta. Chaetomellic acid A is a specific inhibitor of farnesyl-protein transferase. Chaetomellic acid A decreases oxidative stress-induced apoptosis in cells. Chaetomellic acid A reduces renal damage after unilateral ureteral obstruction (UUO) in mice[1][2].

Formula: C19H34O4

References: [1]Nogueira A, et al. The Effects of Long-Term Chaetomellic Acid A Administration on Renal Function and Oxidative Stress in a Rat Model of Renal Mass Reduction. Biomed Res Int. 2017;2017:5125980./[2]Lingham RB, et al. Chaetomella acutiseta produces chaetomellic acids A and B which are reversible inhibitors of farnesyl-protein transferase. Appl Microbiol Biotechnol. 1993 Nov;40(2-3):370-4.

CAS Number: 148796-51-4

Molecular Weight: 326.47

Research Area: Inflammation/Immunology

Target: Farnesyl Transferase

• SKU: MEXHY-134579-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134579-0
• Package Unit: Get quote
• Quantity Unit: STK