Product Description: Chicanine is a lignan compound of Schisandra chinesis, inhibits LPS-induced phosphorylation of p38 MAPK, ERK 1/2 and IκB-α, with anti-inflammatory activity[1].
Applications: COVID-19-immunoregulation
Formula: C20H22O5
References: [1]Chicanine, et al. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in IκBα/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014 Feb 5;724:168-74.
CAS Number: 78919-28-5
Molecular Weight: 342.39
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: ERK;IKK;p38 MAPK