Product Description: Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites of TLR4 and inhibits LPS induced inflammation[1][2].
Applications: COVID-19-immunoregulation
Formula: C36H74Cl6N6O25
References: [1]Qini Zhao, et al. Chitoheptaose Promotes Heart Rehabilitation in a Rat Myocarditis Model by Improving Antioxidant, Anti-Inflammatory, and Antiapoptotic Properties. Oxid Med Cell Longev. 2020 Apr 11;2020:2394704./[2]Santosh K Panda, et al. Chitohexaose activates macrophages by alternate pathway through TLR4 and blocks endotoxemia. PLoS Pathog. 2012;8(5):e1002717.
CAS Number: 127171-88-4
Molecular Weight: 1203.72
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Toll-like Receptor (TLR)