Chlojaponilactone B, CAS 1449382-91-5

Product Description: Chlojaponilactone B is a lindenane-type sesquiterpenoid with anti-inflammatory properties. Chlojaponilactone B suppresses inflammatory responses by inhibiting TLR4 and subsequently decreasing reactive oxygen species (ROS) generation, downregulating the NF-κB, thus reducing the expression of the pro-inflammatory cytokines iNOS, NO, COX-2, IL-6 and TNF-α[1].

Formula: C17H18O4

References: [1]Shaoxia Ye, et al. Chlojaponilactone B Attenuates Lipopolysaccharide-Induced Inflammatory Responses by Suppressing TLR4-Mediated ROS Generation and NF-κB Signaling Pathway. Molecules. 2019 Oct 16;24(20):3731.

CAS Number: 1449382-91-5

Molecular Weight: 286.32

Research Area: Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: NF-κB;Reactive Oxygen Species;Toll-like Receptor (TLR)

• SKU: MEXHY-N8413-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8413-0
• Green Labware: No
• Package Unit: Get quote
• Quantity Unit: STK