Product Description: Cryptanoside A, a cardiac glycoside epoxide, can be isolated from the stems of Cryptolepis dubia. Cryptanoside A has potent cytotoxicity against cancer cells. Cryptanoside A also inhibits Na+/K+-ATPase activity. Cryptanoside A increases the expression of Akt and the p65 subunit of NF-κB[1].
Formula: C30H42O10
References: [1]Ren Y, et al. The Cytotoxic Cardiac Glycoside (-)-Cryptanoside A from the Stems of Cryptolepis dubia and Its Molecular Targets. J Nat Prod. 2023 Jun 23;86(6):1411-1419.
CAS Number: 98570-81-1
Molecular Weight: 562.65
Research Area: Cancer; Inflammation/Immunology; Cardiovascular Disease