Curvularin, CAS 10140-70-2

Product Description: Curvularin, a fungal metabolite and a potent mycotoxin naturally isolated from Curvularia lunata, inhibits cytokine-induced nitric oxide synthase (iNOS), with an IC50 of 9.5 µM[1][2].

Applications: COVID-19-immunoregulation

Formula: C16H20O5

References: [1]Kumar CG, et al. Metabolite profiling and biological activities of bioactive compounds produced by Chrysosporium lobatum strain BK-3 isolated from Kaziranga National Park, Assam, India. Springerplus. 2013 Dec;2(1):122./[2]Yao Y, et al. Sporogen, S14-95, and S-curvularin, three inhibitors of human inducible nitric-oxide synthase expression isolated from fungi. Mol Pharmacol. 2003 Feb;63(2):383-91.

CAS Number: 10140-70-2

Molecular Weight: 292.33

Research Area: Inflammation/Immunology; Infection

Solubility: 10 mM in DMSO

Target: NO Synthase

• SKU: MEXHY-N6770-25
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N6770-25
• Package Unit: 25mg
• Quantity Unit: STK