Product Description: D-Trimannuronic acid, an alginate oligomer is extracted from seaweed. D-Trimannuronic acid can induce TNF‐α secretion by mouse macrophage cell lines. D-Trimannuronic acid can be used for the research of pain and vascular dementia[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C18H26O19
References: [1]Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of vascular dementia. CN106344593A/[2]Geng M, et, al. Application of sodium alginate oligose and derivative to treatment of pain. CN106344595A./[3]Iwamoto M, et, al. Structure-activity relationship of alginate oligosaccharides in the induction of cytokine production from RAW264.7 cells. FEBS Lett. 2005 Aug 15; 579(20): 4423-9.
CAS Number: 66754-13-0
Molecular Weight: 546.39
Research Area: Inflammation/Immunology; Neurological Disease
Solubility: 10 mM in DMSO
Target: TNF Receptor