Formulation: A solid
Formal Name: 4-[2-(4-hydroxy-3-methoxyphenyl)ethyl]-2,6-dimethoxy-phenol
Purity: ≥98%
Formula Markup: C17H20O5
Formula Weight: 304,3
Shelf life (days): 1460
CAS Number: 108853-14-1
Notes: Dendrophenol is a polyphenol that has been found in D. nobile and has diverse biological activities.{66948,66949,66950} It decreases viability of, and induces cell cycle arrest at the S phase in, HCT116 colorectal cancer cells when used at a concentration of 10 µM.{66948} Dendrophenol (3 or 10 µM) inhibits the migration of MDA-MB-231 breast cancer cells.{66949} It inhibits LPS-induced increases in inducible nitric oxide synthase (iNOS), COX-2, hypoxia-inducible factor-1α (HIF-1α), and NF-κB levels and NF-κB nuclear translocation in RAW 264.7 macrophages when used at a concentration of 100 µM.{66950} Dendrophenol (50 or 100 mg/kg per day) reduces tumor size without affecting body weight in an HCT116 mouse xenograft model.{66948} It decreases total lung weight in an MDA-MB-231 mouse xenograft model when administered at a dose of 100 mg/kg per day.{66949}
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