Product Description: Dihydrouracil (5,6-Dihydrouracil), a metabolite of Uracil, can be used as a marker for identification of dihydropyrimidine dehydrogenase (DPD)-deficient[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C4H6N2O2
References: [1]Henricks LM, et, al. Food-effect study on uracil and dihydrouracil plasma levels as marker for dihydropyrimidine dehydrogenase activity in human volunteers. Br J Clin Pharmacol. 2018 Dec;84(12):2761-2769./[2]Jacobs BAW, et, al. The impact of liver resection on the dihydrouracil:uracil plasma ratio in patients with colorectal liver metastases. Eur J Clin Pharmacol. 2018 Jun;74(6):737-744.
CAS Number: 504-07-4
Molecular Weight: 114.10
Compound Purity: 99.95
Research Area: Metabolic Disease
Solubility: DMSO : 14.29 mg/mL (ultrasonic)/H2O : 10 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Endogenous Metabolite
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