Dimethyl malonate, CAS 108-59-8

Product Description: Dimethyl malonate is a competitive inhibitor of succinate dehydrogenase (SDH). Dimethyl malonate is able to cross the blood-brain barrier and hydrolyse to malonate. Dimethyl malonate reduces neuronal apoptosis[1].

Applications: Neuroscience-Neurodegeneration

Formula: C5H8O4

References: [1]Xu J, et al. Inhibiting Succinate Dehydrogenase by Dimethyl Malonate Alleviates Brain Damage in a Rat Model of Cardiac Arrest. Neuroscience. 2018 Nov 21;393:24-32.

CAS Number: 108-59-8

Molecular Weight: 132.11

Compound Purity: 99.92

Research Area: Neurological Disease

Solubility: DMSO : 100 mg/mL (ultrasonic)/H2O : 100 mg/mL (ultrasonic)

Target: Apoptosis

• SKU: MEXHY-Y1787-10.1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-Y1787-10.1
• Green Labware: No
• Package Unit: 10mM/1mL
• Quantity Unit: STK