Product Description: Diphenylamine is a common structure of nonsteroidal anti-inflammatory drugs (NSAIDs) to uncouple mitochondrial oxidative phosphorylation and to cause a decrease in hepatocellular ATP content and hepatocyte injury. Diphenylamine is used as an industrial antioxidant, dye mordant and is also applied in agriculture as a fungicide and antihelmintic[1][2].
Formula: C12H12ClN
References: [1]Safe S, et al. Identification of toxic impurities in commercial diphenylamine. Bull Environ Contam Toxicol. 1977 Feb;17(2):204-7./[2]Masubuchi Y, et al. Possible mechanism of hepatocyte injury induced by diphenylamine and its structurally related nonsteroidal anti-inflammatory drugs. J Pharmacol Exp Ther. 2000 Mar;292(3):982-7.