Dipyrithione, CAS 3696-28-4

Product Description: Dipyrithione is a potent antimicrobial agent. Dipyrithione shows antifungal activity and antiproliferative activity. Dipyrithione induces apoptosis and cycle arrest at G1 phase. Dipyrithione shows anti-inflammatory activity in vivo. Dipyrithione shows anti-tumor activity. Dipyrithione has the potential for the research of dermatophytosis[1][2][3].

Applications: COVID-19-immunoregulation

Formula: C10H8N2O2S2

References: [1]Song X, et al. In vivo antifungal activity of dipyrithione against Trichophyton rubrum on guinea pig dermatophytosis models. Biomed Pharmacother. 2018 Dec;108:558-564./[2]Liu Z, et al. Dipyrithione inhibits lipopolysaccharide-induced iNOS and COX-2 up-regulation in macrophages and protects against endotoxic shock in mice. FEBS Lett. 2008 May 28;582(12):1643-50./[3]Fan Y, et al. Dipyrithione induces cell-cycle arrest and apoptosis in four cancer cell lines in vitro and inhibits tumor growth in a mouse model. BMC Pharmacol Toxicol. 2013 Oct 21;14:54.

CAS Number: 3696-28-4

Molecular Weight: 252.31

Compound Purity: 99.93

Research Area: Cancer; Infection; Inflammation/Immunology

Solubility: DMSO : 10 mg/mL (ultrasonic;warming;heat to 60°C)

Target: Apoptosis;Bacterial;Fungal

• SKU: MEXHY-N8432-5
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8432-5
• Green Labware: No
• Package Unit: 5 mg
• Quantity Unit: STK