Product Description: Eleutherin is a type of naphthoquinone derivative with the protective effect against the injury ofhuman umbilical vein endothelial cells (HUVECs), which can be isolated from the edible bulbs of Eleutherine americana (Hong-Cong)[1].
Applications: Neuroscience-Neuromodulation
Formula: C16H16O4
References: [1]Castro ALG, et, al. Evaluation of the genotoxicity and mutagenicity of isoeleutherin and eleutherin isolated from Eleutherine plicata herb. using bioassays and in silico approaches. Arabian Journal of Chemistry. Volume 14, Issue 4, April 2021, 103084./[2]Krishnan P, et, al. Novel mechanisms of DNA topoisomerase II inhibition by pyranonaphthoquinone derivatives-eleutherin, alpha lapachone, and beta lapachone. Biochem Pharmacol. 2000 Nov 1;60(9):1367-79./[3]Chen D, et al. New naphtoquinones derivatives from the edible bulbs of Eleutherine americana and their protective effect on the injury of human umbilical vein endothelial cells. Fitoterapia. 2019 Jan;132:46-52.
CAS Number: 478-36-4
Molecular Weight: 272.30
Research Area: Cardiovascular Disease
Solubility: 10 mM in DMSO
Target: Topoisomerase
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