Product Description: Epolactaene is a potent Topoisomerase II and DNA Polymerase inhibitor with IC50 values of 10, 25, 94 µM for Topoisomerase II, DNA Polymerase α, DNA Polymerase β, respectively[1].
Formula: C21H27NO6
References: [1]Mizushina Y, et al. Epolactaene, a novel neuritogenic compound in human neuroblastoma cells, selectively inhibits the activities of mammalian DNA polymerases and human DNA topoisomerase II. Biochem Biophys Res Commun. 2000 Jul 5;273(2):784-8.
CAS Number: 167782-17-4
Molecular Weight: 389.44
Research Area: Others
Target: DNA/RNA Synthesis;Topoisomerase