Product Description: Ethinylestradiol is an orally active steroidal estrogen. Ethinylestradiol is widely used in research on menopausal symptoms, gynecological conditions, and certain hormone-sensitive cancers[1].
Applications: Cancer-programmed cell death
Formula: C20H24O2
References: [1]Arnal J F, et al. Ethinylestradiol does not enhance the expression of nitric oxide synthase in bovine endothelial cells but increases the release of bioactive nitric oxide by inhibiting superoxide anion production[J]. Proceedings of the National Academy of Sciences, 1996, 93(9): 4108-4113. /[2]Notch EG, et al. 17alpha-Ethinylestradiol hinders nucleotide excision repair in zebrafish liver cells. Aquat Toxicol. 2009 Dec 13;95(4):273-8./[3]Bertolotti M, et al. Effect of hypocholesterolemic doses of 17 alpha-ethinyl estradiol on cholesterol balance in liver and extrahepatic tissues. J Lipid Res. 1996 Aug;37(8):1812-22. /[4]Mandrup KR, et al. Effects of perinatal ethinyl estradiol exposure in male and female Wistar rats. Reprod Toxicol. 2013 Dec;42:180-91. /[5]Kuhl H. Pharmacology of estrogens and progestogens: influence of different routes of administration. Climacteric. 2005 Aug;8 Suppl 1:3-63.
CAS Number: 57-63-6
Molecular Weight: 296.40
Compound Purity: 99.91
Research Area: Endocrinology; Cancer
Solubility: DMSO : ≥ 100 mg/mL/H2O : < 0.1 mg/mL (ultrasonic;warming;heat to 80°C)
Target: Endogenous Metabolite;Estrogen Receptor/ERR
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