Product Description: Garcinone D, a natural xanthone from mangosteen, promotes the proliferation of C17.2 neural stem cell. Garcinone D increases the protein levels of phosphorylated signal transducer and activator of transcription 3 (p-STAT3), Cyclin D1 and nuclear factor erythroid 2-related factor (Nrf2), heme oxygenase-1 (HO-1) in concentration- and time- dependent manners[1].
Applications: Neuroscience-Neurodegeneration
Formula: C24H28O7
References: [1]Yang X, et al. Garcinone D, a natural xanthone promotes C17.2 neural stem cell proliferation: Possible involvement of STAT3/Cyclin D1 pathway and Nrf2/HO-1 pathway. Neurosci Lett. 2016 Jul 28;626:6-12.
CAS Number: 107390-08-9
Molecular Weight: 428.47
Compound Purity: 99.88
Research Area: Neurological Disease
Solubility: DMSO : 50 mg/mL (ultrasonic)
Target: Keap1-Nrf2;Reactive Oxygen Species;STAT
English
Deutsch
