Product Description: GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of GDP-β-L-fucose. GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM)[1].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C16H23N5Na2O16P2
References: [1]Elling L, et al. Expression, purification and characterization of recombinant phosphomannomutase and GDP-alpha-D-mannose pyrophosphorylase from Salmonella enterica, group B, for the synthesis of GDP-alpha-D-mannose from D-mannose. Glycobiology. 1996 Sep;6(6):591-7.
CAS Number: 103301-73-1
Molecular Weight: 649.30
Compound Purity: 99.92
Research Area: Metabolic Disease
Solubility: DMSO : 11.76 mg/mL (ultrasonic;adjust pH to 3 with 1M HCl)/H2O : 125 mg/mL (ultrasonic)
Target: Endogenous Metabolite
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