Product Description: Glicoricone, a phenolic compound, is isolated from a species of licorice. Glicoricone is an inhibitor of monoamine oxidase (MAO), with an IC50 of 140 μM. Glicoricone binds to estrogen receptor (ER) and shows estrogen antagonist activity[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C21H20O6
References: [1]Hatano T, et, al. Phenolic constituents of licorice. III. Structures of glicoricone and licofuranone, and inhibitory effects of licorice constituents on monoamine oxidase. Chem Pharm Bull (Tokyo). 1991 May;39(5):1238-43./[2]Boonmuen N, et, al. Licorice root components in dietary supplements are selective estrogen receptor modulators with a spectrum of estrogenic and anti-estrogenic activities. Steroids. 2016 Jan;105:42-9.
CAS Number: 161099-37-2
Molecular Weight: 368.38
Compound Purity: 96.0
Research Area: Metabolic Disease
Solubility: 10 mM in DMSO
Target: Estrogen Receptor/ERR;Monoamine Oxidase
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