Product Description: Guanfu base H (Atisinium chloride) is a diterpenoid alkaloid isolated from Aconitum coreanum and has antiplasmodial activity against the malarial Plasmodium falciparum strains TM4/8.2 (wild type) and K1CB1 with IC50 values of 4 μM and 3.6 μM, respectively[1][2].
Applications: COVID-19-immunoregulation
Formula: C22H34ClNO2
References: [1]WU Qiong, et al. Simultaneous Determination of Guanfu Base A,Guanfu Base I and Guanfu Base H in Radix Aconitum coreanum(Lévl) Rapaics by RP-HPLC. Progress in Pharmaceutical Sciences. 2011, 35(5), 230-233./[2]Wangchuk P, et al. Antiplasmodial activity of atisinium chloride from the Bhutanese medicinal plant, Aconitum orochryseum. J Ethnopharmacol. 2010 Aug 9;130(3):559-62.
CAS Number: 4758-99-0
Molecular Weight: 379.96
Compound Purity: 99.80
Research Area: Infection
Solubility: DMSO : 8.33 mg/mL (ultrasonic;warming;heat to 60°C)
Target: Parasite
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