Product Description: HC-Toxin, a cyclic tetrapeptide, is a potent HDAC inhibitor with an IC50 of 30 nM[1]. HC-Toxin induces tumor cell apoptosis and has anticancer effects[2].
Applications: Cancer-programmed cell death
Formula: C21H32N4O6
References: [1]S J Darkin-Rattray, et al. Apicidin: a novel antiprotozoal agent that inhibits parasite histone deacetylase. Proc Natl Acad Sci U S A. 1996 Nov 12;93(23):13143-7./[2]Ki Eun Joung, et al. Antiproliferative effect of trichostatin A and HC-toxin in T47D human breast cancer cells. Arch Pharm Res. 2004 Jun;27(6):640-5.
CAS Number: 83209-65-8
Molecular Weight: 436.50
Compound Purity: 99.26
Research Area: Cancer
Solubility: 10 mM in DMSO
Target: Apoptosis;HDAC