Product Description: Higenamine (Norcoclaurine), a β2-AR agonist, is a key component of the Chinese herb aconite root that prescribes for treating symptoms of heart failure in the oriental Asian countries. Higenamine (Norcoclaurine) has anti-apoptotic effects[1][2].
Applications: Metabolism-protein/nucleotide metabolism
Formula: C16H17NO3
Citations: J Pharmaceut Biomed. 2020, 113870./Nutrients. 2024 May 22.
References: [1]Wu MP, et al. Higenamine protects ischemia/reperfusion induced cardiac injury and myocyte apoptosis through activation of β2-AR/PI3K/AKT signaling pathway. Pharmacol Res. 2016 Feb;104:115-23./[2]Lee SR, et al. Acute oral intake of a higenamine-based dietary supplement increases circulating free fatty acidsand energy expenditure in human subjects. Lipids Health Dis. 2013 Oct 21;12:148.
CAS Number: 5843-65-2
Molecular Weight: 271.31
Compound Purity: 98.03
Research Area: Cardiovascular Disease; Endocrinology
Solubility: DMSO : ≥ 100 mg/mL
Target: Adrenergic Receptor
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