HMBPP, CAS 396726-03-7

Product Description: HMBPP (E-4-Hydroxy-3-methyl-but-2-enyl diphosphate) is an activator for human Vγ9/Vδ2 T cells. HMBPP exhibits phagostimulant property in mosquitos[1][2].

Applications: COVID-19-immunoregulation

Formula: C5H12O8P2

References: [1]Hintz M, et al., Identification of (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate as a major activator for human gammadelta T cells in Escherichia coli. FEBS Lett. 2001 Dec 7;509(2):317-22./[2]Stromsky VE, et al., Plasmodium metabolite HMBPP stimulates feeding of main mosquito vectors on blood and artificial toxic sources. Commun Biol. 2021 Oct 7;4(1):1161.

CAS Number: 396726-03-7

Molecular Weight: 262.09

Research Area: Infection; Inflammation/Immunology

Solubility: 10 mM in DMSO

Target: Nuclear Factor of activated T Cells (NFAT)

• SKU: MEXHY-134891-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-134891-1
• Package Unit: 1 mg
• Quantity Unit: STK