(-)-Hydroxycitric acid lactone, CAS 27750-13-6

Product Description: (-)-Hydroxycitric acid lactone (Garcinia lactone) is an anti-obesity agent and a popular weight loss food supplement. (-)-Hydroxycitric acid lactone is a potent inhibitor of ATP-citrate lyase. (-)-Hydroxycitric acid lactone catalyzes the extramitochondrial cleavage of citrate to oxaloacetate and acetyl-CoA, limits the availability of acetyl-CoA units required for fatty acid synthesis[1][2].

Applications: Metabolism-sugar/lipid metabolism

Formula: C6H6O7

References: [1]Han J, et al. (-)-Hydroxycitric acid reduced fat deposition via regulating lipid metabolism-related geneexpression in broiler chickens. Lipids Health Dis. 2016 Feb 24;15:37./[2]Jena BS, et al. Chemistry and biochemistry of (-)-hydroxycitric acid from Garcinia. J Agric Food Chem. 2002 Jan 2;50(1):10-22.

CAS Number: 27750-13-6

Molecular Weight: 190.11

Compound Purity: 97.0

Research Area: Metabolic Disease

Solubility: DMSO : 250 mg/mL (ultrasonic)

Target: ATP Citrate Lyase

• SKU: MEXHY-N7347-1
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N7347-1
• Green Labware: No
• Package Unit: 1 mg
• Quantity Unit: STK