Product Description: Icariside D2, isolated from Annona glabra fruit, inhibits angiotensin-converting enzyme. Icariside D2 shows significant cytotoxic activity on the HL-60 cell line with the IC50 value of 9.0 ± 1.0 μM. Icariside D2 induces apoptosis [1][2].
Applications: COVID-19-anti-virus
Formula: C14H20O7
References: [1]Nguyen Thi Thu Hien, et al. Chemical Constituents of the Annona Glabra Fruit and Their Cytotoxic Activity. Pharm Biol. 2015;53(11):1602-7./[2]Xue Liu, et al. Metabolic Engineering Escherichia coli for Efficient Production of Icariside D2. Biotechnol Biofuels. 2019 Nov 6;12:261./[3]Jin-YuLi, et al. Three new acylated prenylflavonol glycosides from Epimedium koreanum. Phytochemistry Letters Volume 17, September 2016, Pages 206-212.
CAS Number: 38954-02-8
Molecular Weight: 300.30
Compound Purity: 98.0
Research Area: Cancer; Infection; Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Angiotensin-converting Enzyme (ACE);Apoptosis;HIV
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