Ilicicolin F, CAS 22738-98-3

Product Description: Ilicicolin F is a fungal metabolite that has been found in Fusarium and has diverse biological activities. It inhibits T. vivax alternative oxidase and the E. coli ubiquinol oxidase cytochrome bo (IC50s=0.43 and 0.37 μM, respectively) but not the E. coli ubiquinol oxidase cytochrome bd (IC50=85 μM).2 Ilicicolin F is active against the fungi A. fumigatus and C. albicans (MICs=1.66-3.33 and 6.66-13.33 μg/mL, respectively). It is cytotoxic to HeLa cells with an EC50 value of 0.003 μg/mL.

Applications: COVID-19-immunoregulation

Formula: C25H31ClO6

References: [1]Ellestad, et al. Some new terpenoid metabolites from an unidentified fusarium species. Tetrahedron 25(6), 1323-1334 (1969).

CAS Number: 22738-98-3

Molecular Weight: 462.96

Research Area: Infection

Target: Bacterial

• SKU: MEXHY-N8301-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N8301-0
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• Quantity Unit: STK