Product Description: Isoforskolin is the principle active component of C. forskohlii native to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namely TNF-α, IL-1β, IL-6 and IL-8, in human mononuclear leukocytes. Isoforskolin acts as an anti-inflammatory agent for the treatment of Lyme arthritis[1].
Applications: COVID-19-immunoregulation
Formula: C22H34O7
References: [1]Zhao H, et al. Isoforskolin downregulates proinflammatory responses induced by <i>Borrelia burgdorferi</i> basic membrane protein A.Exp Ther Med. 2017 Dec;14(6):5974-5980.
CAS Number: 64657-21-2
Molecular Weight: 410.50
Compound Purity: 98.0
Research Area: Inflammation/Immunology
Solubility: 10 mM in DMSO
Target: Interleukin Related;TNF Receptor