Isonardosinone, CAS 27062-01-7

Product Description: Isonardosinone is a nardosinone-type sesquiterpenes, which can be isolated from Valerianaceae. Isonardosinone inhibits NF-κB and MAPK signaling pathway, suppresses expression of iNOS and cyclooxygenase-2 (COX-2) in Lipopolysaccharides (HY-D1056)-induced BV2 microglia, exhibits anti-inflammatory activity[1].

Applications: COVID-19-immunoregulation

Formula: C15H22O3

References: [1]Ko W, et al., Nardosinone-Type Sesquiterpenes from the Hexane Fraction of Nardostachys jatamansi Attenuate NF-κB and MAPK Signaling Pathways in Lipopolysaccharide-Stimulated BV2 Microglial Cells. Inflammation. 2018 Aug;41(4):1215-1228.

CAS Number: 27062-01-7

Molecular Weight: 250.33

Research Area: Inflammation/Immunology

Target: COX;NF-κB;NO Synthase;p38 MAPK

• SKU: MEXHY-N9955-0
• Manufacturer: MedChemExpress
• Manufacturer SKU: HY-N9955-0
• Package Unit: Get quote
• Quantity Unit: STK