Product Description: Isoprocurcumenol is a guaiane type sesquiterpene, that can be isolated from Curcuma comosa. Isoprocurcumenol can activate EGFR signaling. Isoprocurcumenol increases the phosphorylation of ERK and AKT. Isoprocurcumenol promotes the proliferation of keratinocytes[1][2][3].
Applications: COVID-19-immunoregulation
Formula: C15H22O2
References: [1]Qu Y, et al. Sesquiterpenes from Curcuma comosa. J Nat Med. 2009 Jan;63(1):102-4./[2]Anuchapreeda S, et al. Cytotoxicity and inhibition of leukemic cell proliferation by sesquiterpenes from rhizomes of Mah-Lueang (Curcuma cf. viridiflora Roxb.). Bioorg Med Chem Lett. 2018 Feb 1;28(3):410-414. /[3]Kwon PK, et al. Isoprocurcumenol Supports Keratinocyte Growth and Survival through Epidermal Growth Factor Receptor Activation. Int J Mol Sci. 2021 Nov 22;22(22):12579.
CAS Number: 102130-90-5
Molecular Weight: 234.33
Compound Purity: 95.41
Research Area: Others
Solubility: DMSO : 2.4 mg/mL (ultrasonic;warming)
Target: Akt;EGFR;ERK